SCHEMBL286054

SCHEMBL286054

Cc1ccc(C(=O)c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
NFE2L2 Q16236 1/20 0.50
ALDH1A1 P00352 1/20 0.50
KMT2A Q03164 3/20 0.49
HTT P42858 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
TP53 P04637 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
HSD11B1 P28845 1/20 0.47
RAB9A P51151 3/20 0.47
RECQL P46063 1/20 0.47
PAX8 Q06710 1/20 0.47
F2 P00734 1/20 0.46
PLAU P00749 1/20 0.46
ELANE P08246 1/20 0.46
MEN1 O00255 2/20 0.45
CSNK2A1 P68400 1/20 0.45
FLT1 P17948 1/20 0.45
FLT4 P35916 1/20 0.45
KDR P35968 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31369141 1.00 LMNA (0.50) LMNANFE2L2ALDH1A1KMT2AHTT
SCHEMBL11610888 0.91 KMT2A (0.50) LMNANFE2L2ALDH1A1KMT2AHTT
SCHEMBL10952578 0.91 ALDH1A1 (0.58) LMNANFE2L2ALDH1A1KMT2AHTT
SCHEMBL14274483 0.89 NPC1 (0.54) NFE2L2ALDH1A1KMT2AHTTSMN1; SMN2
SCHEMBL11756227 0.89 MAPK13 (0.53) NFE2L2ALDH1A1KMT2AHTTSMN1; SMN2
SCHEMBL9856886 0.89 ALDH1A1 (0.62) LMNANFE2L2ALDH1A1KMT2AHTT
SCHEMBL11057757 0.88 CSNK2A1 (0.60) NFE2L2HTTTP53TDP1RAB9A
SCHEMBL11658935 0.88 NFE2L2 (0.42) LMNANFE2L2ALDH1A1KMT2AHTT
SCHEMBL9420260 0.85 NFE2L2 (0.55) LMNANFE2L2ALDH1A1KMT2AHTT
SCHEMBL14029260 0.85 NFE2L2 (0.44) LMNANFE2L2ALDH1A1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059098-A2 PHOTOCATALYTIC CARBOXYLATION OF SUBSTRATES WITH CARBON OXIDE NEW IRIDIUM INC. (US) 2025-03-20 WO disclosed
CN-115179545-A Compositions and articles for additive manufacturing and methods of use thereof 科思创(荷兰)有限公司 2022-10-14 CN disclosed
WO-2022202414-A1 PROTECTIVE TAPE, SEMICONDUCTOR PROTECTIVE TAPE, AND METHOD FOR PRODUCING SEMICONDUCTOR DEVICE 積水化学工業株式会社 2022-09-29 WO disclosed
CN-113302216-A Limonene-based (meth) acrylates for 3D printing 巴斯夫欧洲公司 2021-08-24 CN disclosed
US-10191374-B2 Resist underlayer film-forming composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-01-29 US disclosed
US-20170153548-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-06-01 US disclosed
US-8742028-B2 Solid support for Fmoc-solid phase synthesis of peptide acids MALLINCKRODT LLC (US) 2014-06-03 US disclosed
EP-2427474-A1 SOLID SUPPORT FOR FMOC-SOLID PHASE SYNTHESIS OF PEPTIDE ACIDS Mallinckrodt LLC (US) 2012-03-14 EP disclosed
US-20100286359-A1 Solid Support for FMOC-Solid Phase Synthesis of Peptide Acids MALLINCKRODT INC. (US) 2010-11-11 US disclosed
WO-2010129520-A1 SOLID SUPPORT FOR FMOC-SOLID PHASE SYNTHESIS OF PEPTIDE ACIDS MALLINCKRODT INC. (US) 2010-11-11 WO disclosed
US-4897490-A DERIVATIVES OF BETA-HYDROXY,OMEGA-DIPHENYL,TETRAZOL-5-YL ALK-OMEGA-ENOIC ACID, ESTER OR LACTONE BRISTOL-MEYERS COMPANY (US) 1990-01-30 US disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
WO-1988006584-A1 ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS BRISTOL-MYERS COMPANY (US) 1988-09-07 WO disclosed
US-4769502-A Alkynol type compounds and alcohol-separating process KYOWA HAKKO KOGYO CO., LTD. (JP) 1988-09-06 US disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0178331-A1 ALKYNOL COMPOUNDS AND ALCOHOL SEPARATING AGENTS KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1986-04-23 EP disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
US-4134917-A Method for the denitrosation of organic nitrosamines AMERICAN CYANAMID COMPANY (US) 1979-01-16 US disclosed
US-4071540-A MALEIC OR PHTHALIC CHEVRON RESEARCH COMPANY (US) 1978-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286359-A1 Solid Support for FMOC-Solid Phase Synthesis of Peptide Acids MAX, NPPA, PTMS LMNA 3522/4885NFE2L2 3286/4885ALDH1A1 4730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.