Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12212277 | 0.79 | CYP2A6 (0.41) | CYP2A6ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL241918 | 0.79 | ALDH1A1 (0.69) | CYP2A6ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL1284249 | 0.78 | MAPT (0.48) | CYP2A6CYP1A2CYP2C9CYP2C19KMT2A | |
| Bromide SCHEMBL3103373 | 0.78 | ALDH1A1 (0.67) | CYP2A6ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL20438535 | 0.78 | ALDH1A1 (0.61) | CYP2A6ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL18271203 | 0.78 | ALDH1A1 (0.67) | CYP2A6ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL18085977 | 0.77 | ABL1 (0.45) | CYP2A6ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL557625 | 0.77 | CYP2A6 (0.50) | CYP2A6ALDH1A1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL28190169 | 0.76 | MAPT (0.47) | CYP2A6CYP1A2CYP2C9CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL5521615 | 0.76 | MAPT (0.47) | CYP2A6CYP1A2CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230333019-A1 | TWO-PHOTON FLUORESCENT PROBES FOR SIMULTANEOUSLY DETECTING CALCIUM IONS IN ORGANELLES AND LYSOSOMAL PROTONS | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2023-10-19 | — | — | US | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| WO-2007022263-A1 | FLUOROGENIC PROBES FOR MEDIUM CHAIN ACYL-COA DEHYDROGENASE ( MCAD ) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230333019-A1 | TWO-PHOTON FLUORESCENT PROBES FOR SIMULTANEOUSLY DETECTING CALCIUM IONS IN ORGANELLES AND LYSOSOMAL PROTONS | CHERP, MCU, LETM1 | CYP2A6 4391/4885ALDH1A1 4626/4885HSD17B10 2344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.