SCHEMBL2207929

SCHEMBL2207929

CCCCOc1ccc(OC(=O)C2CCC(CCC)CC2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.49
HTT P42858 1/20 0.49
KMT2A Q03164 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
F2 P00734 1/20 0.45
ELANE P08246 1/20 0.44
HPGD P15428 1/20 0.44
CYP1A2 P05177 2/20 0.43
CYP2D6 P10635 2/20 0.43
KDM4E B2RXH2 1/20 0.43
PDE4A P27815 1/20 0.43
HIF1A Q16665 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
ALDH1A1 P00352 1/20 0.43
ACACB O00763 2/20 0.43
LMNA P02545 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8050529 1.00 SMN1; SMN2 (0.49) SMN1; SMN2HTTKMT2ATDP1F2
SCHEMBL8047981 0.97 NPC1 (0.47) SMN1; SMN2HTTKMT2ATDP1CYP1A2
SCHEMBL9637350 0.97 NPC1 (0.47) SMN1; SMN2HTTKMT2ATDP1CYP1A2
SCHEMBL11422926 0.96 SMN1; SMN2 (0.45) SMN1; SMN2HTTKMT2ATDP1F2
SCHEMBL9591043 0.96 SMN1; SMN2 (0.45) SMN1; SMN2HTTKMT2ATDP1F2
SCHEMBL9591056 0.96 SMN1; SMN2 (0.45) SMN1; SMN2HTTKMT2ATDP1F2
SCHEMBL9591551 0.96 HTT (0.47) SMN1; SMN2HTTKMT2ATDP1F2
SCHEMBL9591541 0.96 HTT (0.47) SMN1; SMN2HTTKMT2ATDP1F2
SCHEMBL9592571 0.95 SMN1; SMN2 (0.44) SMN1; SMN2HTTKMT2ATDP1F2
SCHEMBL9592559 0.95 SMN1; SMN2 (0.44) SMN1; SMN2HTTKMT2ATDP1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 522 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208849-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-26 US disclosed
US-10030198-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2018-07-24 US disclosed
US-20180201836-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-19 US disclosed
US-20180163138-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-06-14 US disclosed
US-9976084-B2 Liquid crystal composition, antioxidant and liquid crystal display device JNC CORPORATION (JP) 2018-05-22 US disclosed
US-20180127651-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-10 US disclosed
US-20180127654-A1 PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-10 US disclosed
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-03 US disclosed
US-20180105749-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-04-19 US disclosed
US-20180086979-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-03-29 US disclosed
EP-0306917-B1 A NEMATIC LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1992-06-17 EP disclosed
US-5102577-A Supertwisted birefringence system CHISSO CORPORATION (JP) 1992-04-07 US disclosed
EP-0281065-B1 LIQUID CRYSTAL COMPOSITION AND DISPLAY ELEMENT CHISSO CORPORATION (JP) 1991-11-27 EP disclosed
US-5055223-A For use in liquid crystal display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-10-08 US disclosed
EP-0393636-A2 Liquid crystal composition and liquid crystal display using said composition CHISSO CORPORATION (JP) 1990-10-24 EP disclosed
US-4917818-A STEEP VOLTAGE TRANSMITTANCE USED IN WATCHES, ELECTRONIC CALCULATORS CHISSO CORPORATION (JP) 1990-04-17 US disclosed
US-4877549-A HIGH MULTIPLEXING DISPLAY DEVICE CHISSO CORPORATION (JP) 1989-10-31 US disclosed
EP-0306917-A2 A nematic liquid crystal composition CHISSO CORPORATION (JP) 1989-03-15 EP disclosed
EP-0281065-A1 Liquid crystal composition and display element CHISSO CORPORATION (JP) 1988-09-07 EP disclosed
US-4279770-A Liquid crystal 2,3-dicyano-hydroquinone derivatives CHISSO CORPORATION (JP) 1981-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE YBX1, PIEZO1, C1S SMN1; SMN2 3837/4885HTT 2921/4885KMT2A 2759/4885
US-20180127654-A1 PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DRD1, PLD1, DRD2 SMN1; SMN2 4549/4885HTT 2146/4885KMT2A 2766/4885
US-20180127651-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE LASP1, PYCARD, CRYAA SMN1; SMN2 4060/4885HTT 1259/4885KMT2A 2402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.