Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257838 | 0.84 | TDP1 (0.68) | TDP1LMNAKMT2AMAPK1MEN1 | |
| SCHEMBL22080313 | 0.82 | TDP1 (0.48) | TDP1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL22079956 | 0.79 | HTT (0.41) | TDP1LMNAKMT2AMEN1MAPT | |
| SCHEMBL18382537 | 0.77 | PLK1 (0.67) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL22079960 | 0.76 | TDP1 (0.40) | TDP1LMNAKMT2AMEN1MAPT | |
| SCHEMBL26153240 | 0.73 | LMNA (0.46) | LMNAMAPTGAAHTT | |
| SCHEMBL22080312 | 0.72 | TDP1 (0.52) | TDP1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL22079887 | 0.72 | TDP1 (0.48) | TDP1LMNAKMT2AMEN1MAPT | |
| SCHEMBL5317757 | 0.72 | TDP1 (0.65) | TDP1LMNAKMT2AMEN1MAPT | |
| SCHEMBL22080247 | 0.71 | TDP1 (0.49) | TDP1LMNAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200181223-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181223-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | TDP1 4783/4885LMNA 3090/4885KMT2A 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.