Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22079982 | 0.84 | TDP1 (0.52) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL22080432 | 0.82 | TDP1 (0.61) | TDP1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL24257837 | 0.81 | TP53 (0.48) | TDP1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL22079909 | 0.80 | AKT1 (0.48) | TDP1KDM4E | |
| SCHEMBL22080431 | 0.78 | KDM4E (0.54) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL26786077 | 0.78 | HDAC1 (0.46) | TDP1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL5317757 | 0.77 | TDP1 (0.65) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8752453 | 0.74 | KMT2A (0.91) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL24257833 | 0.74 | ALDH1A1 (0.56) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8240251 | 0.73 | TDP1 (0.60) | TDP1KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | TDP1 4783/4885MAPT 3611/4885KMT2A 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.