SCHEMBL22082133

SCHEMBL22082133

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C)c(NS(=O)(=O)C(F)(F)F)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 9/20 0.44
▸ PTGS2 P35354 9/20 0.44
▸ CA2 P00918 5/20 0.38
▸ CA1 P00915 1/20 0.38
▸ CYP2C9 P11712 1/20 0.36
▸ PTPN11 Q06124 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.35
▸ IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26418314 0.84 MAPT (0.43) PTGS1PTGS2CA2CA1
SCHEMBL26418297 0.81 PTGS1 (0.41) PTGS1PTGS2CA2CA1NPSR1
SCHEMBL20257192 0.79 CA2 (0.50) PTGS1PTGS2CA2CA1PTPN11
SCHEMBL17774980 0.69 PTPN11 (0.67) PTGS1PTGS2CA2CA1PTPN11
SCHEMBL122373 0.69 MAPK1 (0.66) PTGS1PTGS2CYP2C9
SCHEMBL7039101 0.69 NPC1 (0.47) PTGS1PTGS2CA2CA1CYP2C9
SCHEMBL11182644 0.68 PTGS1 (0.41) PTGS1PTGS2CA2CA1PTPN11
SCHEMBL11380592 0.68 LMNA (0.47) PTGS1PTGS2CYP2C9
SCHEMBL11511786 0.68 MAPK1 (0.64) PTGS1PTGS2CYP2C9
SCHEMBL26418233 0.67 MAPT (0.48) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021162115-A1 LAMINATE, DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE 富士フイルム株式会社 2021-08-19 — — WO disclosed
WO-2021132674-A1 LIGHT ABSORBING FILTER, OPTICAL FILTER, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE, AND LIQUID CRYSTAL DISPLAY DEVICE 富士フイルム株式会社 2021-07-01 — — WO disclosed
WO-2021014973-A1 WAVELENGTH-SELECTIVE ABSORPTION FILTER AND ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE 富士フイルム株式会社 2021-01-28 — — WO disclosed
WO-2020116642-A1 RESIN COMPOSITION, OPTICAL FILTER, IMAGE DISPLAY DEVICE, SOLID-STATE IMAGING ELEMENT, AND DYE MIXTURE 富士フイルム株式会社 2020-06-11 — — WO disclosed
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