Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378345 | 0.99 | LMNA (0.46) | LMNASMN1; SMN2MAPK1HTTKMT2A | |
| SCHEMBL11376209 | 0.99 | LMNA (0.46) | LMNASMN1; SMN2MAPK1HTTKMT2A | |
| SCHEMBL11459823 | 0.82 | KMT2A (0.49) | LMNASMN1; SMN2MAPK1HTTKMT2A | |
| SCHEMBL11191391 | 0.81 | KMT2A (0.53) | LMNASMN1; SMN2MAPK1HTTKMT2A | |
| SCHEMBL11467996 | 0.80 | KMT2A (0.44) | LMNAMAPK1HTTKMT2AMEN1 | |
| SCHEMBL11382212 | 0.79 | ALDH1A1 (0.41) | LMNASMN1; SMN2MAPK1HTTKMT2A | |
| SCHEMBL11488482 | 0.78 | PTGS2 (0.40) | PTGS1PTGS2GHSRBRD4JAK2 | |
| SCHEMBL11182644 | 0.78 | PTGS1 (0.41) | SMN1; SMN2KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL11179768 | 0.78 | ALDH1A1 (0.40) | LMNASMN1; SMN2MAPK1HTTKMT2A | |
| SCHEMBL11382285 | 0.78 | ALDH1A1 (0.40) | LMNASMN1; SMN2MAPK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294606-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1981-10-13 | — | — | US | claimed |