SCHEMBL2208255

SCHEMBL2208255

CCCCCC1CCC(C(=O)Oc2ccc(OCC)cc2)CC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
USP2 O75604 1/20 0.45
TP53 P04637 1/20 0.45
TSHR P16473 1/20 0.45
F2 P00734 1/20 0.43
ELANE P08246 1/20 0.43
PKM P14618 2/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
MEN1 O00255 2/20 0.40
NPY2R P49146 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
ITGB3 P05106 1/20 0.39
ITGA2B P08514 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8046614 1.00 KMT2A (0.46) KMT2AHTTSMN1; SMN2TDP1USP2
SCHEMBL3278501 0.99 KMT2A (0.45) KMT2AHTTSMN1; SMN2TDP1USP2
SCHEMBL9402522 0.99 KMT2A (0.45) KMT2AHTTSMN1; SMN2TDP1USP2
SCHEMBL11408119 0.96 KMT2A (0.43) KMT2AHTTSMN1; SMN2TDP1USP2
SCHEMBL2604713 0.96 KMT2A (0.47) KMT2AHTTSMN1; SMN2TDP1USP2
SCHEMBL2785540 0.96 KMT2A (0.47) KMT2AHTTSMN1; SMN2TDP1USP2
SCHEMBL11405474 0.95 KMT2A (0.42) KMT2AHTTSMN1; SMN2TDP1USP2
SCHEMBL11411629 0.95 KMT2A (0.42) KMT2AHTTSMN1; SMN2TDP1USP2
SCHEMBL11411114 0.95 KMT2A (0.42) KMT2AHTTSMN1; SMN2TDP1USP2
SCHEMBL11405762 0.92 KMT2A (0.44) KMT2AHTTSMN1; SMN2TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4400059-A Liquid crystal display device HITACHI, LTD. (JP) 1983-08-23 US claimed
JP-55089377-A None JP disclosed
US-20180208849-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-26 US disclosed
US-10030198-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2018-07-24 US disclosed
US-20180201836-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-19 US disclosed
US-20180163138-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-06-14 US disclosed
US-9976084-B2 Liquid crystal composition, antioxidant and liquid crystal display device JNC CORPORATION (JP) 2018-05-22 US disclosed
US-20180127651-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-10 US disclosed
US-20180127654-A1 PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-10 US disclosed
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-03 US disclosed
EP-0393636-A2 Liquid crystal composition and liquid crystal display using said composition CHISSO CORPORATION (JP) 1990-10-24 EP disclosed
US-4917818-A STEEP VOLTAGE TRANSMITTANCE USED IN WATCHES, ELECTRONIC CALCULATORS CHISSO CORPORATION (JP) 1990-04-17 US disclosed
US-4877549-A HIGH MULTIPLEXING DISPLAY DEVICE CHISSO CORPORATION (JP) 1989-10-31 US disclosed
EP-0087963-B1 PHTHALONITRILE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM Hitachi, Ltd. (JP) 1989-05-03 EP disclosed
EP-0306917-A2 A nematic liquid crystal composition CHISSO CORPORATION (JP) 1989-03-15 EP disclosed
EP-0281065-A1 Liquid crystal composition and display element CHISSO CORPORATION (JP) 1988-09-07 EP disclosed
US-4479885-A Phthalonitrile derivatives and a liquid crystal composition containing the same HITACHI, LTD. (JP) 1984-10-30 US disclosed
EP-0087963-A2 Phthalonitrile derivatives and liquid crystal compositions containing them Hitachi, Ltd. (JP) 1983-09-07 EP disclosed
US-4400059-A Liquid crystal display device HITACHI, LTD. (JP) 1983-08-23 US disclosed
JP-S5589377-A LIQUID CRYSTAL COMPOSITION HITACHI LTD 1980-07-05 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE YBX1, PIEZO1, C1S KMT2A 2759/4885HTT 2921/4885SMN1; SMN2 3837/4885
US-20180127654-A1 PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DRD1, PLD1, DRD2 KMT2A 2766/4885HTT 2146/4885SMN1; SMN2 4549/4885
US-20180127651-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE LASP1, PYCARD, CRYAA KMT2A 2402/4885HTT 1259/4885SMN1; SMN2 4060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.