Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 5/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22084414 | 0.88 | LPL (0.43) | LPLLIPGHPGDLMNA | |
| SCHEMBL22084416 | 0.79 | HPGD (0.38) | HPGDLMNA | |
| SCHEMBL22084393 | 0.76 | HPGD (0.40) | HPGDLMNA | |
| SCHEMBL22084413 | 0.76 | HPGD (0.38) | HPGDLMNA | |
| SCHEMBL22084415 | 0.74 | HPGD (0.42) | SMN1; SMN2HPGDLMNA | |
| SCHEMBL22084380 | 0.74 | HPGD (0.41) | HPGD | |
| SCHEMBL22084696 | 0.72 | HPGD (0.45) | HPGD | |
| SCHEMBL22084420 | 0.72 | HPGD (0.39) | HPGDLMNA | |
| SCHEMBL22084391 | 0.72 | HPGD (0.39) | HPGDLMNA | |
| SCHEMBL21231761 | 0.71 | LIPG (0.56) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117938-A1 | PRODRUGS OF ANTI-CANCER AND ANTI-AUTOIMMUNE DISEASES THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2020-06-11 | — | — | WO | disclosed |