Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 13/20 | 0.46 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22089164 | 0.79 | CYP11B2 (0.40) | — | |
| SCHEMBL20902271 | 0.74 | NAAA (0.62) | NAAAFAAH | |
| SCHEMBL22089162 | 0.73 | NAAA (0.40) | NAAA | |
| SCHEMBL4522108 | 0.73 | DAO (0.50) | — | |
| SCHEMBL21364182 | 0.71 | NAAA (0.54) | NAAAFAAH | |
| SCHEMBL7269558 | 0.71 | NAAA (0.81) | NAAAFAAH | |
| SCHEMBL30773945 | 0.68 | HRH3 (0.41) | NAAAFAAH | |
| SCHEMBL4511435 | 0.67 | CYP4F2 (0.47) | — | |
| SCHEMBL20902222 | 0.67 | NAAA (0.51) | NAAAFAAH | |
| SCHEMBL26621163 | 0.67 | DAO (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027593-B1 | PIPERAZINE DERIVATIVES AS HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME (US) | 2020-06-10 | — | — | EP | disclosed |