Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 4/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30773984 | 0.90 | GPR142 (0.41) | HRH3NAAASLC22A6SLC22A8SLC22A12 | |
| SCHEMBL30774782 | 0.84 | MAPT (0.50) | RAB9AKDM4E | |
| SCHEMBL30774039 | 0.80 | GPR142 (0.53) | NAAACNR1GPR142FAAH | |
| SCHEMBL30774365 | 0.72 | STAT3 (0.41) | HRH3NAAASLC22A12 | |
| SCHEMBL22088899 | 0.68 | NAAA (0.46) | NAAAFAAH | |
| SCHEMBL1191643 | 0.66 | SLC22A12 (0.55) | NAAASLC22A6SLC22A8SLC22A12FAAH | |
| SCHEMBL1587910 | 0.66 | HRH3 (0.64) | HRH3NAAACNR1ENPP2 | |
| SCHEMBL30774767 | 0.65 | SLC22A6 (0.51) | NAAASLC22A6SLC22A8SLC22A12RAB9A | |
| SCHEMBL22813668 | 0.65 | HRH3 (0.67) | HRH3NAAACNR1 | |
| SCHEMBL4375445 | 0.65 | HRH3 (0.60) | HRH3CNR1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024061371-A1 | ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 广州威诺森医药科技有限公司 | 2024-03-28 | — | — | WO | claimed |
| WO-2024061371-A1 | ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 广州威诺森医药科技有限公司 | 2024-03-28 | — | — | WO | disclosed |