Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 3/20 | 0.30 |
| ▸ | JAK1 | P23458 | 3/20 | 0.30 |
| ▸ | TYK2 | P29597 | 3/20 | 0.30 |
| ▸ | JAK3 | P52333 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5438523 | 0.78 | ALDH1A1 (0.41) | HCAR1ALDH1A1CNOT7MEN1KMT2A | |
| SCHEMBL880201 | 0.67 | PNP (0.48) | ADORA3 | |
| SCHEMBL8338180 | 0.65 | ALDH1A1 (0.35) | ALDH1A1ADORA3ADORA2BLMNAALB | |
| SCHEMBL1992699 | 0.65 | ALDH1A1 (0.43) | ALDH1A1ADORA3ADORA2BLMNA | |
| SCHEMBL8354948 | 0.65 | ADORA2A (0.33) | ALDH1A1ADORA2B | |
| SCHEMBL10518132 | 0.65 | ALDH1A1 (0.38) | ALDH1A1ADORA2B | |
| SCHEMBL30670576 | 0.63 | ADRB1 (0.55) | ADORA3LMNA | |
| SCHEMBL4560684 | 0.62 | ADORA3 (0.35) | HCAR1ALDH1A1ADORA3ADORA2BJAK2 | |
| SCHEMBL12411008 | 0.61 | MEN1 (0.45) | ALDH1A1MEN1KMT2AADORA2BMAPK1 | |
| SCHEMBL1993927 | 0.61 | ADORA2A (0.41) | ALDH1A1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308567-A1 | ANITIVIRAL PRODRUGS OF ENTECAVIR (ETV) AND FORMULATIONS THEREOF | The Scripps Research Institute (US) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022198195-A1 | ANITIVIRAL PRODRUGS OF ENTECAVIR (ETV) AND FORMULATIONS THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-09-22 | — | — | WO | disclosed |
| EP-3894395-A2 | CYCLOPENTYL NUCLEOSIDE ANALOGS AS ANTI-VIRALS | Janssen BioPharma, Inc. (US) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020121123-A2 | CYCLOPENTYL NUCLEOSIDE ANALOGS AS ANTI-VIRALS | Janssen Biopharma, Inc. (US) | 2020-06-18 | — | — | WO | disclosed |