Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2212464 | 1.00 | SMYD2 (0.52) | SMYD2ADRB2 | |
| SCHEMBL2212701 | 0.95 | SMYD2 (0.55) | SMYD2ADRB2 | |
| SCHEMBL2213109 | 0.95 | SMYD2 (0.55) | SMYD2ADRB2 | |
| SCHEMBL2209883 | 0.95 | SMYD2 (0.55) | SMYD2ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2213357 | 0.94 | SMYD2 (0.52) | SMYD2ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2213234 | 0.93 | SMYD2 (0.51) | SMYD2ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2208356 | 0.93 | ADRB2 (0.58) | SMYD2ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2212522 | 0.92 | SMYD2 (0.52) | SMYD2ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2211966 | 0.92 | ADRB2 (0.49) | SMYD2ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2209373 | 0.91 | ADRB2 (0.57) | SMYD2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121642-B1 | 4-HYDR0XY-2-0X0-2, 3 -DIHYDRO- 1, 3-BENZOTHIAZOL- 7YL COMPOUNDS FOR MODULATION OF B2-ADRENORECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2011-07-27 | — | — | EP | disclosed |
| US-20100249200-A1 | Novel Compounds 569 | ASTRAZENECA AB (SE) | 2010-09-30 | — | — | US | disclosed |
| US-7700782-B2 | Compounds 569 | ASTRAZENECA AB (SE) | 2010-04-20 | — | — | US | disclosed |
| US-20100022491-A1 | 4-HYDROXY-2-OXO-2,3-DIHYDRO-1,3-BENZOTHIAZOL-7YL COMPOUNDS FOR MODULATION OF B2-ADRENORECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2010-01-28 | — | — | US | disclosed |
| US-20080207698-A1 | Novel Compounds 569 | ASTRAZENECA AB (SE) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207698-A1 | Novel Compounds 569 | RB1, CNKSR1, CDK9 | SMYD2 3840/4885ADRB2 1549/4885 |
| US-20100022491-A1 | 4-HYDROXY-2-OXO-2,3-DIHYDRO-1,3-BENZOTHIAZOL-7YL COMPOUNDS FOR MODULATION OF B2-ADRENORECEPTOR ACTIVITY | ADRB2, ADRB1, ADRA2C | SMYD2 3657/4885ADRB2 1/4885 |
| US-20100249200-A1 | Novel Compounds 569 | RB1, CNKSR1, CDK9 | SMYD2 3840/4885ADRB2 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.