Sulisobenzone

Sulisobenzone

SCHEMBL2209368

CC(C)[O-].CC(C)[O-].CC(C)[O-].COc1cc(O)c(C(=O)c2ccccc2)cc1S(=O)(=O)[O-].[Ti+4]

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.71
MAPT P10636 5/20 0.71
KMT2A Q03164 4/20 0.71
ALDH1A1 P00352 3/20 0.71
HPGD P15428 3/20 0.61
KDM4E B2RXH2 2/20 0.61
HSD17B10 Q99714 2/20 0.61
CYP3A4 P08684 1/20 0.61
RECQL P46063 1/20 0.61
HTT P42858 3/20 0.48
MAPK1 P28482 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2D6 P10635 2/20 0.48
CYP2C19 P33261 2/20 0.48
PGR P06401 1/20 0.48
SLC6A2 P23975 1/20 0.48
PDE4A P27815 1/20 0.48
HRH1 P35367 1/20 0.48
SLC6A3 Q01959 1/20 0.48
PDE4D Q08499 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulisobenzone SCHEMBL10621756 0.94 LMNA (0.76) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL10723288 0.94 LMNA (0.76) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL29378407 0.94 LMNA (0.76) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL11277588 0.94 LMNA (0.76) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL338882 0.94 LMNA (0.76) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL10491696 0.94 LMNA (0.76) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL6295947 0.94 LMNA (0.76) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL28588923 0.93 LMNA (0.74) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL5147287 0.86 LMNA (0.65) LMNAMAPTKMT2AALDH1A1HPGD
Sulisobenzone SCHEMBL2365646 0.83 MAPT (0.61) LMNAMAPTKMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7982063-B2 Mineral/organic composite material CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2011-07-19 US disclosed
US-20100121088-A1 Mineral/Organic Composite Material CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2010-05-13 US disclosed
US-20090104135-A1 Use of Mineral/Organic Composite Material in the Form of an Ultraviolet Radiation Protective Agent LVMH RECHERCHE (FR) 2009-04-23 US disclosed