Sulisobenzone

Sulisobenzone

SCHEMBL2365646

COc1cc(O)c(C(=O)c2ccccc2)cc1S(=O)(=O)[O-].Clc1ccc([S+](c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.61
LMNA P02545 6/20 0.61
ALDH1A1 P00352 3/20 0.61
KMT2A Q03164 2/20 0.61
HPGD P15428 2/20 0.53
KDM4E B2RXH2 2/20 0.53
HSD17B10 Q99714 2/20 0.53
CYP3A4 P08684 1/20 0.53
RECQL P46063 1/20 0.53
HTT P42858 3/20 0.42
MAPK1 P28482 2/20 0.42
CYP1A2 P05177 1/20 0.42
PGR P06401 1/20 0.42
CYP2D6 P10635 1/20 0.42
SLC6A2 P23975 1/20 0.42
PDE4A P27815 1/20 0.42
CYP2C19 P33261 1/20 0.42
HRH1 P35367 1/20 0.42
SLC6A3 Q01959 1/20 0.42
PDE4D Q08499 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulisobenzone SCHEMBL338882 0.87 LMNA (0.76) MAPTLMNAALDH1A1KMT2AHPGD
Sulisobenzone SCHEMBL11277588 0.87 LMNA (0.76) MAPTLMNAALDH1A1KMT2AHPGD
Sulisobenzone SCHEMBL29378407 0.87 LMNA (0.76) MAPTLMNAALDH1A1KMT2AHPGD
Sulisobenzone SCHEMBL10723288 0.87 LMNA (0.76) MAPTLMNAALDH1A1KMT2AHPGD
Sulisobenzone SCHEMBL6295947 0.87 LMNA (0.76) MAPTLMNAALDH1A1KMT2AHPGD
Sulisobenzone SCHEMBL10491696 0.87 LMNA (0.76) MAPTLMNAALDH1A1KMT2AHPGD
Sulisobenzone SCHEMBL10621756 0.87 LMNA (0.76) MAPTLMNAALDH1A1KMT2AHPGD
Sulisobenzone SCHEMBL28588923 0.85 LMNA (0.74) MAPTLMNAALDH1A1KMT2AHPGD
Sulisobenzone SCHEMBL2209368 0.83 LMNA (0.71) MAPTLMNAALDH1A1KMT2AHPGD
SCHEMBL2365652 0.80 MAPT (0.63) MAPTLMNAALDH1A1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9046774-B2 Positive-working lithographic printing plate precursor for infrared laser and process for making lithographic printing plate FUJIFILM CORPORATION (JP) 2015-06-02 US disclosed
US-20140065538-A1 POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR FOR INFRARED LASER AND PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2014-03-06 US disclosed
US-8632951-B2 Positive-working lithographic printing plate precursor for infrared laser and process for making lithographic printing plate FUJIFILM CORPORATION (JP) 2014-01-21 US disclosed
EP-2365389-B1 Positive-working lithographic printing plate precursor for infrared laser and process for making lithographic printing plate FUJIFILM CORP (JP) 2013-01-16 EP disclosed
EP-2365389-A1 Positive-working lithographic printing plate precursor for infrared laser and process for making lithographic printing plate Fujifilm Corporation (JP) 2011-09-14 EP disclosed
US-20110217656-A1 POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR FOR INFRARED LASER AND PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-09-08 US disclosed