Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Sulisobenzone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.51 |
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 0.51 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.41 |
| ▸ | NOD2 known ✓ | Q9HC29 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulisobenzone SCHEMBL29378407 | 1.00 | LMNA (0.76) | LMNAMAPTKMT2AALDH1A1HPGD | |
| Sulisobenzone SCHEMBL28588923 | 0.99 | LMNA (0.74) | LMNAMAPTKMT2AALDH1A1HPGD | |
| Sulisobenzone SCHEMBL11277588 | 0.97 | LMNA (0.76) | LMNAMAPTKMT2AALDH1A1HPGD | |
| Sulisobenzone SCHEMBL6295947 | 0.97 | LMNA (0.76) | LMNAMAPTKMT2AALDH1A1HPGD | |
| Sulisobenzone SCHEMBL10621756 | 0.97 | LMNA (0.76) | LMNAMAPTKMT2AALDH1A1HPGD | |
| Sulisobenzone SCHEMBL10491696 | 0.97 | LMNA (0.76) | LMNAMAPTKMT2AALDH1A1HPGD | |
| Sulisobenzone SCHEMBL10723288 | 0.97 | LMNA (0.76) | LMNAMAPTKMT2AALDH1A1HPGD | |
| Sulisobenzone SCHEMBL2209368 | 0.94 | LMNA (0.71) | LMNAMAPTKMT2AALDH1A1HPGD | |
| Sulisobenzone SCHEMBL5147287 | 0.90 | LMNA (0.65) | LMNAMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL240880 | 0.87 | LMNA (0.56) | LMNAMAPTKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1057 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117801714-A | Photovoltaic module packaging adhesive film and preparation method and application thereof | 极电光能有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-115304863-A | Antibacterial plastic film and production process thereof | 江苏益森新材料有限公司 | 2022-11-08 | — | — | CN | claimed |
| US-11390808-B2 | Singlet oxygen scavenger | SHISEIDO COMPANY, LTD. (JP) | 2022-07-19 | — | — | US | claimed |
| EP-3773444-B1 | COSMETIC COMPOSITION FOR A FAST SWEAT EVAPORATION | BEIERSDORF AG (DE) | 2022-03-02 | — | — | EP | claimed |
| CN-113773569-A | Antibacterial bath ball and preparation method thereof | 衢州市洁妮肤日用品有限责任公司 | 2021-12-10 | — | — | CN | claimed |
| CN-113123011-B | Elastic ribbon with massage function | 江西绣丽织带有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-113123011-A | Elastic ribbon with massage function | 江西绣丽织带有限公司 | 2021-07-16 | — | — | CN | claimed |
| US-20210030649-A1 | COSMETIC COMPOSITION FOR WET SKIN | BEIERSDORF AG (DE) | 2021-02-04 | — | — | US | claimed |
| CN-107629310-B | Supermolecule intercalation structure light stabilizer and preparation method thereof | 北京化工大学 | 2020-07-24 | — | — | CN | claimed |
| US-20200140754-A1 | SINGLET OXYGEN SCAVENGER | SHISEIDO COMPANY, LTD. (JP) | 2020-05-07 | — | — | US | claimed |
| US-20140335039-A1 | NOVEL OIL-IN-WATER EMULSIONS ENRICHED WITH SALT WHICH ARE HIGHLY VISCOUS AND STABLE OVER TIME | SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUS- TRIES CHIMIQUES SEPPIC (FR) | 2014-11-13 | — | — | US | claimed |
| WO-2013189702-A2 | COSMETIC AND DERMATOLOGICAL PREPARATION CONTAINING ONE OR MORE SUBSTANCES WHICH MODULATE THE GENE / PROTEIN FOR THE ENDO180 RECEPTOR | BEIERSDORF AG (DE) | 2013-12-27 | — | — | WO | claimed |
| CN-103334296-A | Antibacterial finishing agent for cotton textiles and preparation method thereof | NINGBO YOUNGOR TECHNOLOGY CO LTD | 2013-10-02 | — | — | CN | claimed |
| CN-101529244-B | Ozone detecting element | NIPPON TELEGRAPH AND TELEPHONE CORP. (JP) | 2011-12-07 | — | — | CN | claimed |
| CN-101744733-A | Organic-inorganic complex with uv-blocking effect, a preparation method thereof, and a use of the same | WOONGJIN COWAY CO LTD | 2010-06-23 | — | — | CN | claimed |
| CN-101529244-A | Ozone detecting element | NIPPON TELEGRAPH & TELEPHONE (JP) | 2009-09-09 | — | — | CN | claimed |
| CN-1713889-A | Composition for external use for skin and method of using the same | KOSE CORP (JP) | 2005-12-28 | — | — | CN | claimed |
| EP-1570839-A1 | COMPOSITION FOR PREPARATION FOR EXTERNAL USE ON SKIN AND METHOD OF USING THE SAME | Kosé Corporation (JP) | 2005-09-07 | — | — | EP | claimed |
| US-6077520-A | ANTI-AGING TOPICAL COMPOSITION INCLUDING AT LEAST ONE OF SULFONYLETHYLENEAMINE OR MERCAPTOSULFONYLETHYLENEAMINE COMPOUNDS OF GIVEN FORMULA AND SPECIFIED ULTRAVIOLET LIGHT PROTECTIVE AGENTS | SHISEIDO COMPANY, LTD. (JP) | 2000-06-20 | — | — | US | claimed |
| US-6046330-A | Complexes of ultraviolet absorbers and quaternary ammonium compounds which are substantially free from unwanted salts | MILLIKEN & COMPANY | 2000-04-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140335039-A1 | NOVEL OIL-IN-WATER EMULSIONS ENRICHED WITH SALT WHICH ARE HIGHLY VISCOUS AND STABLE OVER TIME | ALG1, MGAT3, CSGALNACT1 | PDE4A 4333/4885PDE4D 4484/4885PTGS1 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.