Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14518833 | 0.74 | PDE10A (0.42) | ELANETLR7KDM4EMAPTCYP1A2 | |
| SCHEMBL5690187 | 0.71 | CYP1A2 (0.57) | ELANEMAPTCYP1A2 | |
| SCHEMBL117318 | 0.71 | CYP1A2 (0.57) | ELANEMAPTCYP1A2 | |
| SCHEMBL29399169 | 0.71 | CYP1A2 (0.57) | ELANEMAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL28287683 | 0.69 | CYP1A2 (0.56) | ELANECYP1A2 | |
| SCHEMBL22094948 | 0.69 | BACE1 (0.49) | NOS3NOS1NOS2KDM4EMAPT | |
| SCHEMBL26508289 | 0.69 | EGFR (0.37) | NOS3NOS1NOS2TSHRMAPK1 | |
| SCHEMBL22104955 | 0.69 | PDE10A (0.35) | NOS3NOS1NOS2TSHRMAPK1 | |
| SCHEMBL18199915 | 0.69 | CCR1 (0.50) | NOS3NOS1NOS2TSHRMAPK1 | |
| SCHEMBL23420779 | 0.68 | NOS3 (0.33) | NOS3NOS1NOS2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12291504-B2 | Small molecule inhibition of sulfotransferase SULT1A3 | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2025-05-06 | — | — | US | disclosed |
| US-20220024876-A1 | SMALL MOLECULE INHIBITION OF SULFOTRANSFERASE SULT1A3 | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-01-27 | — | — | US | disclosed |
| WO-2020123482-A1 | SMALL MOLECULE INHIBITION OF SULFOTRANSFERASE SULT1A3 | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024876-A1 | SMALL MOLECULE INHIBITION OF SULFOTRANSFERASE SULT1A3 | SULT1A1, SULT2A1, SULT1E1 | NOS3 153/4885NOS1 909/4885NOS2 899/4885 |
| US-12291504-B2 | Small molecule inhibition of sulfotransferase SULT1A3 | SULT1A1, SULT2A1, SULT1E1 | NOS3 153/4885NOS1 909/4885NOS2 899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.