SCHEMBL2209528

SCHEMBL2209528

SCc1ccccc1-c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.60
FOLH1 Q04609 3/20 0.52
KMT2A Q03164 1/20 0.50
PDCD1 Q15116 1/20 0.47
CD274 Q9NZQ7 1/20 0.47
IDO1 P14902 2/20 0.46
HTR7 P34969 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
ALDH1A1 P00352 3/20 0.42
HSD17B10 Q99714 2/20 0.42
HPGD P15428 1/20 0.42
BCL2L1 Q07817 1/20 0.42
CYP2A6 P11509 1/20 0.42
MAPK1 P28482 1/20 0.42
KCNA5 P22460 1/20 0.42
KCNH2 Q12809 1/20 0.42
DCLRE1A Q6PJP8 1/20 0.41
DCLRE1B Q9H816 1/20 0.41
PTGER1 P34995 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6701464 0.91 DPP4 (0.50) DPP4FOLH1KMT2APDCD1CD274
SCHEMBL16231221 0.82 ALDH1A1 (0.44) DPP4FOLH1KMT2AIDO1ALDH1A1
SCHEMBL1129835 0.82 KCNA5 (0.50) DPP4FOLH1KMT2AIDO1CYP11B1
SCHEMBL28389139 0.82 ABL1 (0.50) DPP4FOLH1KMT2AIDO1BCL2L1
SCHEMBL6701461 0.82 DPP4 (0.47) DPP4FOLH1KMT2APDCD1CD274
SCHEMBL28655366 0.82 DPP4 (0.47) DPP4FOLH1KMT2APDCD1CD274
SCHEMBL27900782 0.82 FOLH1 (0.50) DPP4FOLH1KMT2APDCD1CD274
SCHEMBL21153739 0.81 CD274 (0.69) DPP4FOLH1KMT2APDCD1CD274
SCHEMBL31387875 0.79 DPP4 (0.65) DPP4FOLH1KMT2APDCD1CD274
SCHEMBL11333152 0.79 DPP4 (0.65) DPP4FOLH1KMT2APDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117915999-A Epoxide-activated substrates and hydrophobic interaction chromatography membranes made therefrom 唐纳森公司 2024-04-19 CN claimed
CN-117396270-A Aqueous dispersion of microcapsules, and use thereof 高砂香料工业株式会社 2024-01-12 CN claimed
CN-116253944-B Corrosion-resistant high-strength composite cable 广东康明达实业有限公司 2023-11-10 CN claimed
CN-116253944-A Corrosion-resistant high-strength composite cable 广东康明达实业有限公司 2023-06-13 CN claimed
CN-115838452-A Resin, preparation method, resin composition, optical film, adhesive and polymer 华为技术有限公司 2023-03-24 CN claimed
CN-114839366-A Nanoparticle for detecting antigen protein and preparation method thereof 南方科技大学 2022-08-02 CN claimed
CN-114270562-A Electrochemical cells and assemblies comprising thiol-group containing materials 赛昂能源有限公司 2022-04-01 CN claimed
CN-114222555-A Additives for colorants and methods of use thereof 生活实验公司 2022-03-22 CN claimed
CN-109153172-B Photocurable polymer, photocurable polymer composition and photolithography process including the same 索尔维特殊聚合物美国有限责任公司 2020-12-25 CN claimed
CN-112040926-A Covalent treatment of keratin-containing materials with thiols 生活实验公司 2020-12-04 CN claimed
CN-111655750-A Thiourethane-based aerogels 汉高股份有限及两合公司 2020-09-11 CN claimed
CN-103079557-A Bismuth-thiols as antibacterial agents for biomedical and other uses including treatment of bacterial biofilms MICROBION CORP 2013-05-01 CN claimed
CN-112040926-B Covalent treatment of keratin-containing materials with thiols 生活实验公司 2024-07-02 CN disclosed
CN-118139653-A Composition and composite article for forming nitric oxide 斯特里莱国家有限责任公司 2024-06-04 CN disclosed
CN-117915999-A Epoxide-activated substrates and hydrophobic interaction chromatography membranes made therefrom 唐纳森公司 2024-04-19 CN disclosed
CN-117396270-A Aqueous dispersion of microcapsules, and use thereof 高砂香料工业株式会社 2024-01-12 CN disclosed
US-6548512-B1 Pyrazole derivatives such as 1-(3-amidinophenyl)-3-methyl-2-((5-(2'-aminosulfonylphenyl-1-yl)pyrimidin-2 -yl)aminocarbonyl)pyrazole; treating thromboembolic disorders BRISTOL-MYERS SQUIBB PHARMA COMPANY 2003-04-15 US disclosed
US-6020357-A CARDIOVASCULAR DISORDERS; ANTCOAGULANTS DUPONT PHARMACEUTICALS COMPANY (US) 2000-02-01 US disclosed
EP-0946508-A1 NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS Du Pont Pharmaceuticals Company (US) 1999-10-06 EP disclosed
WO-1998028269-A1 NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS DU PONT PHARMACEUTICALS COMPANY (US) 1998-07-02 WO disclosed