Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.37 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29424918 | 0.83 | DPP4 (0.47) | DPP4ALDH1A1MAPK1FOLH1PDCD1 | |
| SCHEMBL30625954 | 0.83 | PDCD1 (0.60) | DPP4ALDH1A1MAPK1FOLH1PDCD1 | |
| SCHEMBL3392132 | 0.83 | DPP4 (0.47) | DPP4ALDH1A1MAPK1FOLH1PDCD1 | |
| SCHEMBL10982314 | 0.83 | PDCD1 (0.60) | DPP4ALDH1A1MAPK1FOLH1PDCD1 | |
| SCHEMBL2209528 | 0.82 | DPP4 (0.60) | DPP4ALDH1A1MAPK1FOLH1PDCD1 | |
| SCHEMBL27907921 | 0.82 | GABRA1 (0.61) | DPP4ALDH1A1MAPK1FOLH1PDCD1 | |
| SCHEMBL429933 | 0.79 | ALDH1A1 (0.62) | DPP4ALDH1A1MAPK1PDCD1CD274 | |
| SCHEMBL6701461 | 0.79 | DPP4 (0.47) | DPP4ALDH1A1MAPK1FOLH1PDCD1 | |
| SCHEMBL27900782 | 0.79 | FOLH1 (0.50) | DPP4ALDH1A1MAPK1FOLH1PDCD1 | |
| SCHEMBL6701464 | 0.78 | DPP4 (0.50) | DPP4ALDH1A1MAPK1FOLH1PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582971-B | Small molecule immunosuppressant, preparation method and application thereof | 北京康辰药业股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-113582971-A | Small molecule immunosuppressant, preparation method and application thereof | 北京康辰药业股份有限公司 | 2021-11-02 | — | — | CN | disclosed |