Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 5/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951322 | 0.80 | GPR119 (0.33) | ABCB1GPR119GRM5ALDH1A1GLA | |
| SCHEMBL588780 | 0.78 | KDM4A (0.43) | — | |
| SCHEMBL31298183 | 0.78 | HDAC1 (0.47) | ABCB1GPR119ALDH1A1 | |
| Hydrochloric Acid SCHEMBL589320 | 0.77 | KDM4A (0.42) | — | |
| SCHEMBL4951522 | 0.77 | NR1D1 (0.35) | GPR119GRM5NR1D1PDK1PDK2 | |
| SCHEMBL5869066 | 0.77 | STING1 (0.38) | ABCB1GPR119ALDH1A1GLA | |
| SCHEMBL31298142 | 0.76 | L3MBTL1 (0.43) | MTNR1AMTNR1BNR1D1CCNB2CCNE2 | |
| SCHEMBL13269488 | 0.75 | TP53 (0.43) | ALDH1A1MTNR1AMTNR1BNR1D1 | |
| SCHEMBL19770173 | 0.74 | MTNR1A (0.35) | MTNR1AMTNR1BNR1D1CCNB2CCNE2 | |
| SCHEMBL4951324 | 0.73 | GPR119 (0.36) | ABCB1GPR119ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1808440-B1 | Non-covalent inhibitors of urokinase and blood vessel formation | WILEX AG (DE) | 2011-07-27 | — | — | EP | disclosed |
| EP-1808440-A1 | Non-covalent inhibitors of urokinase and blood vessel formation | Wilex AG (DE) | 2007-07-18 | — | — | EP | disclosed |
| EP-1182207-B1 | Non-covalent inhibitors of urokinase and blood vessel formation | DENDREON CORP (US) | 2007-04-18 | — | — | EP | disclosed |
| US-6586405-B2 | Therapy for blood disorders | CORVAS INTERNATIONAL, INC. | 2003-07-01 | — | — | US | disclosed |
| US-6541467-B1 | And at P1 have a six-membered heterocyclic ring having two ring nitrogen ring atoms and the remainder of the ring atoms carbon atoms. | CORVAS INTERNATIONAL, INC. | 2003-04-01 | — | — | US | disclosed |
| US-20020037857-A1 | Non-covalent inhibitors of urokinase and blood vessel formation | CORVAS INTERNATIONAL, INC. | 2002-03-28 | — | — | US | disclosed |
| EP-1182207-A2 | Non-covalent inhibitors of urokinase and blood vessel formation | CORVAS INTERNATIONAL, INC. (US) | 2002-02-27 | — | — | EP | disclosed |
| WO-2002014349-A2 | NON-COVALENT INHIBITORS OF UROKINASE AND BLOOD VESSEL FORMATION | CORVAS INTERNATIONAL, INC. (US) | 2002-02-21 | — | — | WO | disclosed |
| WO-2001079261-A1 | TETRAHYDRO-AZEPINONE DERIVATIVES AS THROMBIN INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037857-A1 | Non-covalent inhibitors of urokinase and blood vessel formation | PLAU, PLAT, PLG | ABCB1 4746/4885GPR119 1992/4885GRM5 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.