SCHEMBL22097539

SCHEMBL22097539

O=C(OC1CCCC(C(=O)NS(=O)(=O)C(F)(F)F)C1)c1c(I)ccc(I)c1I

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ VCP P55072 1/20 0.31
▸ SERPINE1 P05121 1/20 0.31
▸ LOXL2 Q9Y4K0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22097538 0.87 VCP (0.35) LMNAMAPTSMN1; SMN2NPSR1VCP
SCHEMBL26343823 0.83 SERPINE1 (0.32) VCPSERPINE1LOXL2
SCHEMBL22166144 0.71 — —
SCHEMBL22503049 0.70 HDAC8 (0.39) SMN1; SMN2VCP
SCHEMBL26343818 0.70 VCP (0.35) VCP
SCHEMBL22097548 0.69 MAPK1 (0.35) SMN1; SMN2VCP
SCHEMBL22097549 0.69 KMT2A (0.36) LMNASMN1; SMN2NPSR1
SCHEMBL24465304 0.68 TP53 (0.32) VCP
SCHEMBL22503052 0.67 HDAC8 (0.43) LMNASMN1; SMN2VCP
SCHEMBL26353754 0.66 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11774853-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-03 — — US disclosed
US-11774853-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-03 — — US disclosed
US-20200192222-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-06-18 — — US disclosed
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