SCHEMBL22100154

SCHEMBL22100154

c1ccc2c(c1)sc1c(-c3cccc4c5ccccc5n(-c5nccc6c5sc5ccccc56)c34)nccc12

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.34
DUSP3 P51452 1/20 0.34
MCL1 Q07820 5/20 0.33
PARP14 Q460N5 1/20 0.33
ADK P55263 1/20 0.31
PRKDC P78527 2/20 0.31
PIK3CD O00329 1/20 0.31
PIK3CB P42338 1/20 0.31
GPR3 P46089 1/20 0.30
HTT P42858 1/20 0.30
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22100002 0.90 PARP14 (0.39) ALOX5DUSP3PARP14ADKPRKDC
SCHEMBL22074640 0.85 ALOX5 (0.33) ALOX5DUSP3MCL1GPR3
SCHEMBL17997058 0.85 ALOX5 (0.36) ALOX5DUSP3MCL1PARP14ADK
SCHEMBL22100039 0.85 ALOX5 (0.33) ALOX5DUSP3PARP14PRKDCPIK3CD
SCHEMBL21316763 0.85 GPR3 (0.39) ALOX5PARP14GPR3
SCHEMBL22074656 0.84 TP53 (0.33) ALOX5DUSP3MCL1PRKDCGPR3
SCHEMBL22409585 0.83 ACHE (0.32) ALOX5MCL1PARP14GPR3
SCHEMBL22100025 0.83 ALOX5 (0.34) ALOX5DUSP3PARP14PRKDCPIK3CD
SCHEMBL22100157 0.83 PRKDC (0.34) ALOX5DUSP3PARP14PRKDCPIK3CD
SCHEMBL22100029 0.83 ALOX5 (0.36) ALOX5DUSP3PARP14PRKDCPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11834459-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-11834459-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-20200190103-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION 2020-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200190103-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES RPS4X, MLX, RPS4Y1 ALOX5 3051/4885DUSP3 2417/4885MCL1 1912/4885
US-11834459-B2 Host materials for electroluminescent devices RPS4X, MLX, RPS4Y1 ALOX5 3051/4885DUSP3 2417/4885MCL1 1912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.