Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22075835 | 0.87 | ALDH1A1 (0.58) | KDM4EKMT2AMAPTALDH1A1PKM | |
| SCHEMBL29195725 | 0.82 | SMN1; SMN2 (0.56) | RAB9ANPC1KDM4ESMN1; SMN2GAA | |
| SCHEMBL10953580 | 0.76 | RAB9A (0.47) | RAB9ANPC1KDM4ESMN1; SMN2GAA | |
| SCHEMBL15971476 | 0.76 | HSD17B2 (0.58) | RAB9ANPC1KDM4ESMN1; SMN2GAA | |
| SCHEMBL6171410 | 0.76 | ALDH1A1 (0.63) | RAB9ANPC1KDM4ESMN1; SMN2GAA | |
| SCHEMBL22833162 | 0.75 | ALDH1A1 (0.54) | RAB9ANPC1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL22114012 | 0.75 | ALDH1A1 (0.48) | KDM4EGAAKMT2AMAPTALDH1A1 | |
| SCHEMBL5739672 | 0.74 | MTNR1A (0.38) | RAB9ANPC1KDM4ESMN1; SMN2GAA | |
| SCHEMBL19003293 | 0.74 | CA12 (0.57) | RAB9ANPC1KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL6171237 | 0.73 | PTGER4 (0.62) | RAB9ANPC1KDM4EGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3894416-B1 | FERROPORTIN INHIBITORS AND METHODS OF USE | GLOBAL BLOOD THERAPEUTICS INC (US) | 2022-11-09 | — | — | EP | disclosed |
| WO-2020123850-A1 | FERROPORTIN INHIBITORS AND METHODS OF USE | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2020-06-18 | — | — | WO | disclosed |