Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808223 | 0.79 | SMN1; SMN2 (0.58) | NPC1ALDH1A1TRPM8SMN1; SMN2LMNA | |
| SCHEMBL8629811 | 0.78 | CCR5 (0.52) | CCR5NPC1ALDH1A1TRPM8SMN1; SMN2 | |
| SCHEMBL14139451 | 0.76 | LCK (0.58) | NPC1ALDH1A1TRPM8SMN1; SMN2LMNA | |
| SCHEMBL17046111 | 0.74 | TRPV1 (0.47) | CCR5NPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16307375 | 0.73 | CCR5 (0.53) | CCR5NPC1ALDH1A1TRPM8SMN1; SMN2 | |
| SCHEMBL4485628 | 0.73 | TRPV1 (0.48) | THRB | |
| SCHEMBL17046170 | 0.72 | DRD3 (0.46) | CCR5NPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14099270 | 0.72 | ALDH1A1 (0.48) | NPC1ALDH1A1TRPM8SMN1; SMN2LMNA | |
| SCHEMBL27863544 | 0.72 | LCK (0.54) | NPC1ALDH1A1TRPM8SMN1; SMN2LMNA | |
| SCHEMBL16784701 | 0.71 | CYP2D6 (0.38) | CCR5ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501761-B1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2020-06-17 | — | — | EP | disclosed |