Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22100705 | 0.79 | CCR5 (0.52) | SMN1; SMN2LMNAALDH1A1TRPM8MAPT | |
| SCHEMBL4181822 | 0.78 | SLC6A2 (0.42) | SMN1; SMN2LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL9057107 | 0.78 | G6PC1 (0.40) | SMN1; SMN2LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL8629811 | 0.78 | CCR5 (0.52) | SMN1; SMN2LMNAALDH1A1TRPM8MAPT | |
| SCHEMBL9057974 | 0.78 | G6PC1 (0.42) | SMN1; SMN2LMNAHPGDSLC6A2SLC6A4 | |
| SCHEMBL9057644 | 0.78 | G6PC1 (0.42) | SMN1; SMN2LMNAHPGDSLC6A2SLC6A4 | |
| SCHEMBL10891206 | 0.77 | G6PC1 (0.50) | SMN1; SMN2ALDH1A1KDM4EHPGDCHRM2 | |
| SCHEMBL4476467 | 0.77 | G6PC1 (0.54) | SMN1; SMN2ALDH1A1KDM4EHPGDSLC6A2 | |
| SCHEMBL433534 | 0.77 | G6PC1 (0.38) | SMN1; SMN2LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL9056621 | 0.74 | TAAR1 (0.45) | LMNAALDH1A1KDM4EHPGDSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |