Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208903 | 1.00 | ALDH1A1 (0.40) | ALDH1A1CYP2D6TSHRMAOAMAOB | |
| SCHEMBL1643462 | 0.72 | OPRM1 (0.39) | CYP2D6OPRM1OPRL1 | |
| SCHEMBL28665811 | 0.70 | — | — | |
| SCHEMBL2390648 | 0.69 | OPRM1 (0.37) | OPRM1OPRL1 | |
| SCHEMBL2395154 | 0.69 | OPRM1 (0.39) | ALDH1A1CYP2D6OPRM1OPRL1HSD17B10 | |
| SCHEMBL443388 | 0.68 | — | — | |
| SCHEMBL443387 | 0.68 | — | — | |
| SCHEMBL3856902 | 0.68 | MAOA (0.44) | MAOAMAOB | |
| SCHEMBL2395090 | 0.68 | OPRM1 (0.35) | OPRM1OPRL1 | |
| SCHEMBL2390992 | 0.68 | KDM4E (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7982053-B2 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC (US) | 2011-07-19 | — | — | US | disclosed |