Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101422 | 0.84 | MAOB (0.32) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL22101435 | 0.84 | TSHR (0.30) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL22101184 | 0.83 | CRHR1 (0.31) | GRIN1GRIN2AALDH1A1LMNA | |
| SCHEMBL22393763 | 0.82 | — | — | |
| SCHEMBL22101706 | 0.79 | HTR1A (0.32) | RXFP1LMNA | |
| SCHEMBL22101905 | 0.79 | PDE2A (0.31) | KDM4EALDH1A1HSD17B10TSHRRXFP1 | |
| SCHEMBL22101725 | 0.78 | GRIN1 (0.40) | GRIN1GRIN2AKDM4EALDH1A1HPGD | |
| SCHEMBL23099580 | 0.77 | NPC1 (0.33) | ALDH1A1HPGDPKMRXFP1LMNA | |
| SCHEMBL19189767 | 0.77 | ENPP2 (0.30) | — | |
| SCHEMBL22101707 | 0.77 | ALDH1A1 (0.32) | KDM4EALDH1A1HPGDHSD17B10RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |