Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101539 | 0.87 | FFAR4 (0.35) | RXFP1POLBMAPTKDM4ENPC1 | |
| SCHEMBL22101541 | 0.85 | MAPT (0.35) | RXFP1POLBMAPTLMNAKDM4E | |
| SCHEMBL22393587 | 0.84 | THRB (0.33) | THRBKMT2AMAPTTP53LTB4R | |
| SCHEMBL22101540 | 0.81 | CYP2C9 (0.35) | RXFP1LMNAKDM4EALDH1A1RAB9A | |
| SCHEMBL22101706 | 0.78 | HTR1A (0.32) | THRBKMT2ARXFP1P2RX7MAPT | |
| SCHEMBL22101472 | 0.73 | FFAR4 (0.32) | ALDH1A1 | |
| SCHEMBL22101725 | 0.72 | GRIN1 (0.40) | THRBRXFP1POLBMAPTKDM4E | |
| SCHEMBL22393591 | 0.72 | MAPT (0.33) | MAPTTP53 | |
| SCHEMBL22101868 | 0.71 | KDM4E (0.35) | RXFP1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL22101522 | 0.70 | PIK3CB (0.37) | PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |