Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | NT5E | P21589 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | CASP6 | P55212 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | GNG2 | P59768 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22683201 | 0.95 | RAPGEF4 (0.50) | ALDH1A1NT5ETSHRRAPGEF4MAPT | |
| SCHEMBL22701348 | 0.89 | RAPGEF4 (0.50) | ALDH1A1NT5ETSHRRAPGEF4MAPT | |
| SCHEMBL10720084 | 0.87 | RAPGEF4 (0.62) | ALDH1A1NT5ETSHRRAPGEF4MAPT | |
| SCHEMBL11335315 | 0.87 | RAPGEF4 (0.62) | ALDH1A1NT5ETSHRRAPGEF4MAPT | |
| SCHEMBL6051237 | 0.84 | ALDH1A1 (0.75) | ALDH1A1NT5ETSHRRAPGEF4MAPT | |
| SCHEMBL20268581 | 0.82 | MAPT (0.59) | ALDH1A1RAPGEF4MAPTKDM4ETDP1 | |
| SCHEMBL22102764 | 0.80 | RAPGEF4 (0.38) | ALDH1A1NT5ETSHRRAPGEF4MAPT | |
| SCHEMBL27658915 | 0.78 | GAA (0.57) | ALDH1A1NT5ETSHRRAPGEF4MAPT | |
| SCHEMBL20285584 | 0.78 | MAPT (0.51) | ALDH1A1RAPGEF4MAPTKDM4ETDP1 | |
| SCHEMBL17715464 | 0.77 | TSHR (0.75) | ALDH1A1NT5ETSHRRAPGEF4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3554466-B1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | OREAL (FR) | 2020-11-25 | — | — | EP | claimed |
| US-10927259-B2 | Dissymmetric azomethine direct dyes and process for their preparation, cosmetic composition comprising at least one such dye and use thereof | L'OREAL (FR) | 2021-02-23 | — | — | US | disclosed |
| EP-3554466-B1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | OREAL (FR) | 2020-11-25 | — | — | EP | disclosed |
| EP-3554466-B1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | OREAL (FR) | 2020-11-25 | — | — | EP | disclosed |
| US-20200190329-A1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | L'OREAL (FR) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927259-B2 | Dissymmetric azomethine direct dyes and process for their preparation, cosmetic composition comprising at least one such dye and use thereof | KRT18, DSG1, IK | ALDH1A1 754/4885NT5E 1645/4885TSHR 2280/4885 |
| US-20200190329-A1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | KRT18, DSG1, IK | ALDH1A1 754/4885NT5E 1645/4885TSHR 2280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.