Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NT5E | P21589 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22102772 | 0.89 | ALDH1A1 (0.58) | RAPGEF4ALDH1A1NT5ETSHRKDM4E | |
| SCHEMBL22683201 | 0.84 | RAPGEF4 (0.50) | RAPGEF4ALDH1A1NT5ETSHRKDM4E | |
| SCHEMBL11335315 | 0.80 | RAPGEF4 (0.62) | RAPGEF4ALDH1A1NT5ETSHRKDM4E | |
| SCHEMBL10720084 | 0.80 | RAPGEF4 (0.62) | RAPGEF4ALDH1A1NT5ETSHRKDM4E | |
| SCHEMBL6051237 | 0.77 | ALDH1A1 (0.75) | RAPGEF4ALDH1A1NT5ETSHRKDM4E | |
| SCHEMBL27658915 | 0.74 | GAA (0.57) | RAPGEF4ALDH1A1NT5ETSHRKDM4E | |
| SCHEMBL22683200 | 0.73 | MAPT (0.61) | RAPGEF4ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL22701334 | 0.73 | TSHR (0.51) | ALDH1A1TSHRKDM4EMAPTGAA | |
| SCHEMBL9620899 | 0.73 | ALDH1A1 (0.56) | ALDH1A1NT5ETSHRKDM4EMAPT | |
| SCHEMBL20268581 | 0.72 | MAPT (0.59) | RAPGEF4ALDH1A1KDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3554466-B1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | OREAL (FR) | 2020-11-25 | — | — | EP | disclosed |