Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | OGG1 | O15527 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22104944 | 0.87 | TDP1 (0.80) | TDP1OGG1LMNATP53MAPT | |
| SCHEMBL22104943 | 0.86 | TP53 (0.78) | TDP1OGG1LMNATP53NR3C1 | |
| SCHEMBL22104671 | 0.84 | OGG1 (0.72) | TDP1OGG1LMNATP53NR3C1 | |
| SCHEMBL22104668 | 0.84 | OGG1 (0.80) | TDP1OGG1LMNATP53NR3C1 | |
| SCHEMBL22104638 | 0.82 | OGG1 (1.00) | TDP1OGG1LMNATP53MAPT | |
| SCHEMBL10241674 | 0.81 | NOTUM (0.66) | TDP1LMNATP53PKMSMN1; SMN2 | |
| SCHEMBL22104670 | 0.80 | LMNA (0.84) | TDP1OGG1LMNATP53NR3C1 | |
| SCHEMBL22104674 | 0.80 | ALDH1A1 (0.82) | TDP1OGG1LMNATP53MAPT | |
| SCHEMBL22104676 | 0.80 | ALDH1A1 (0.72) | TDP1OGG1LMNATP53PKM | |
| SCHEMBL29817571 | 0.78 | RORC (0.79) | LMNATP53MAPTNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190034-A1 | Inhibitors of Base Excision Repair Activity and Therapeutic Methods Based Thereon | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190034-A1 | Inhibitors of Base Excision Repair Activity and Therapeutic Methods Based Thereon | OGG1, UNG, MPG | TDP1 19/4885OGG1 1/4885LMNA 2093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.