Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.50 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22104703 | 0.80 | OGG1 (0.95) | OGG1MAPTLMNAHTTKMT2A | |
| SCHEMBL22104660 | 0.78 | OGG1 (0.95) | OGG1MAPTLMNAHTTKMT2A | |
| SCHEMBL9959550 | 0.78 | NLRP3 (0.50) | OGG1MAPTLMNAHTTKMT2A | |
| SCHEMBL22104863 | 0.77 | OGG1 (0.74) | OGG1MAPTLMNAHTTKMT2A | |
| SCHEMBL8308177 | 0.74 | F10 (0.64) | — | |
| SCHEMBL22104844 | 0.74 | OGG1 (0.70) | OGG1MAPTLMNAHTTKMT2A | |
| SCHEMBL22104707 | 0.73 | OGG1 (0.86) | OGG1MAPTLMNAHTTKDM4E | |
| SCHEMBL22104949 | 0.73 | OGG1 (0.84) | OGG1MAPTLMNAHTTKMT2A | |
| Hydrochloric Acid SCHEMBL8312274 | 0.73 | F10 (0.61) | — | |
| SCHEMBL11095226 | 0.72 | DRD2 (0.65) | MAPTLMNASMN1; SMN2KCNA1KCNAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190034-A1 | Inhibitors of Base Excision Repair Activity and Therapeutic Methods Based Thereon | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190034-A1 | Inhibitors of Base Excision Repair Activity and Therapeutic Methods Based Thereon | OGG1, UNG, MPG | OGG1 1/4885MAPT 3985/4885LMNA 2093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.