Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PARN | O95453 | 1/20 | 0.36 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22105567 | 0.82 | TSHR (0.45) | ALDH1A1TSHRGDACYP11B2SMN1; SMN2 | |
| SCHEMBL21499645 | 0.70 | GDA (0.46) | ALDH1A1TSHRGDAHPGDCYP11B2 | |
| SCHEMBL23974592 | 0.67 | TSHR (0.57) | ALDH1A1TSHRGDAHPGDCYP11B2 | |
| SCHEMBL22105440 | 0.63 | BRD4 (0.62) | ALDH1A1HPGDSMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL16068380 | 0.61 | CYP11B2 (0.54) | ALDH1A1TSHRGDACYP11B2SMN1; SMN2 | |
| SCHEMBL5745154 | 0.60 | GDA (0.51) | ALDH1A1TSHRGDAHPGDCYP11B2 | |
| SCHEMBL7985407 | 0.58 | CNOT7 (0.54) | ALDH1A1HPGDSMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL5341956 | 0.58 | SMN1; SMN2 (0.50) | ALDH1A1TSHRHPGDCYP11B2SMN1; SMN2 | |
| SCHEMBL21499649 | 0.58 | MAPK1 (0.43) | ALDH1A1TSHRCYP11B2SMN1; SMN2CYP1A2 | |
| SCHEMBL30595217 | 0.57 | PARN (0.54) | TSHRHPGDCYP11B2SMN1; SMN2ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11198696-B2 | Substituted xanthines as inhibitors of transient receptor potential cation channel subfamily c, member 5 activity | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-12-14 | — | — | US | disclosed |
| US-20200190093-A1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190093-A1 | SUBSTITUTED XANTHINE DERIVATIVES | TRPC5, TRPC4, TRPM5 | ALDH1A1 869/4885TSHR 1665/4885GDA 2668/4885 |
| US-11198696-B2 | Substituted xanthines as inhibitors of transient receptor potential cation channel subfamily c, member 5 activity | TRPC5, TRPM5, TRPC4 | ALDH1A1 1568/4885TSHR 1011/4885GDA 2588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.