SCHEMBL22106976

SCHEMBL22106976

c1ccc(-c2ccc3c4ccccc4n(-c4cccc5c4oc4ccc(-c6cccc7c6sc6ccccc67)cc45)c3c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 11/20 0.44
ALOX5 P09917 2/20 0.42
PIK3CD O00329 2/20 0.34
PIK3CB P42338 2/20 0.34
BRD4 O60885 1/20 0.34
PIK3CA P42336 1/20 0.34
MTOR P42345 1/20 0.34
PIK3CG P48736 1/20 0.34
KCNH2 Q12809 1/20 0.34
BRDT Q58F21 1/20 0.34
LIMK1 P53667 1/20 0.32
ESR2 Q92731 1/20 0.31
PLA2G2A P14555 2/20 0.31
PLA2G4A P47712 2/20 0.31
TNKS O95271 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
PIM3 Q86V86 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22107008 0.95 ALOX5 (0.43) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL22107274 0.93 ALOX5 (0.45) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL22107494 0.93 ALOX5 (0.48) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL22106970 0.90 PRKDC (0.33) PRKDCLIMK1PLA2G2APLA2G4APIM3
SCHEMBL22106978 0.90 PRKDC (0.33) PRKDCLIMK1PLA2G2APLA2G4APLA2G10
SCHEMBL22107028 0.90 PRKDC (0.34) PRKDCALOX5BRDTPLA2G2APLA2G4A
SCHEMBL22107111 0.89 PRKDC (0.42) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL25671861 0.88 ALOX5 (0.42) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL22107057 0.88 ALOX5 (0.39) PRKDCALOX5PIK3CDPIK3CBBRD4
SCHEMBL17248336 0.87 ALOX5 (0.46) PRKDCALOX5PIK3CDPIK3CBBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11683982-B2 Organic compound having excellent thermal resistance property and luminescent property, organic light emitting diode and organic light emitting device having the compound LG DISPLAY CO., LTD. (KR) 2023-06-20 US disclosed
US-11683982-B2 Organic compound having excellent thermal resistance property and luminescent property, organic light emitting diode and organic light emitting device having the compound LG DISPLAY CO., LTD. (KR) 2023-06-20 US disclosed
US-20200194685-A1 ORGANIC COMPOUND HAVING EXCELLENT THERMAL RESISTANCE PROPERTY AND LUMINESCENT PROPERTY, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND LG DISPLAY CO., LTD. (KR) 2020-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11683982-B2 Organic compound having excellent thermal resistance property and luminescent property, organic light emitting diode and organic light emitting device having the compound DDT, DBF4, L3MBTL4 PRKDC 979/4885ALOX5 2142/4885PIK3CD 2697/4885
US-20200194685-A1 ORGANIC COMPOUND HAVING EXCELLENT THERMAL RESISTANCE PROPERTY AND LUMINESCENT PROPERTY, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND DDT, DBF4, L3MBTL4 PRKDC 979/4885ALOX5 2142/4885PIK3CD 2697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.