SCHEMBL22106978

SCHEMBL22106978

c1ccc(-c2ccc3c4ccccc4n(-c4cccc5c4oc4ccc(-c6ccc7c(c6)sc6ccccc67)cc45)c3c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 4/20 0.33
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
PLA2G10 O15496 1/20 0.32
LIMK1 P53667 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
PDE3B Q13370 1/20 0.31
PDE7A Q13946 1/20 0.31
PDE3A Q14432 1/20 0.31
PTPRF P10586 1/20 0.30
PTPN2 P17706 1/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22106970 0.96 PRKDC (0.33) PRKDCPLA2G2APLA2G4APLA2G10LIMK1
SCHEMBL22107002 0.96 PRKDC (0.33) PRKDCPLA2G2APLA2G4APLA2G10LIMK1
SCHEMBL22107495 0.95 PRKDC (0.35) PRKDCPLA2G2APLA2G4APLA2G10ALDH1A1
SCHEMBL22107268 0.94 PLA2G2A (0.34) PRKDCPLA2G2APLA2G4APLA2G10LIMK1
SCHEMBL26508255 0.91 PRKDC (0.33) PRKDCALDH1A1MAPTHPGDRAB9A
SCHEMBL22107003 0.91 PLA2G2A (0.34) PRKDCPLA2G2APLA2G4APLA2G10LIMK1
SCHEMBL22106976 0.90 PRKDC (0.44) PRKDCPLA2G2APLA2G4APLA2G10LIMK1
SCHEMBL22107028 0.89 PRKDC (0.34) PRKDCPLA2G2APLA2G4APTPRFPTPN2
SCHEMBL22107496 0.89 PRKDC (0.33) PRKDCPLA2G2APLA2G4APLA2G10ALDH1A1
SCHEMBL26741300 0.89 PTPRF (0.34) PRKDCALDH1A1MAPTHPGDPTPRF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11683982-B2 Organic compound having excellent thermal resistance property and luminescent property, organic light emitting diode and organic light emitting device having the compound LG DISPLAY CO., LTD. (KR) 2023-06-20 US disclosed
US-11683982-B2 Organic compound having excellent thermal resistance property and luminescent property, organic light emitting diode and organic light emitting device having the compound LG DISPLAY CO., LTD. (KR) 2023-06-20 US disclosed
US-20200194685-A1 ORGANIC COMPOUND HAVING EXCELLENT THERMAL RESISTANCE PROPERTY AND LUMINESCENT PROPERTY, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND LG DISPLAY CO., LTD. (KR) 2020-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11683982-B2 Organic compound having excellent thermal resistance property and luminescent property, organic light emitting diode and organic light emitting device having the compound DDT, DBF4, L3MBTL4 PRKDC 979/4885PLA2G2A 4702/4885PLA2G4A 4412/4885
US-20200194685-A1 ORGANIC COMPOUND HAVING EXCELLENT THERMAL RESISTANCE PROPERTY AND LUMINESCENT PROPERTY, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND DDT, DBF4, L3MBTL4 PRKDC 979/4885PLA2G2A 4702/4885PLA2G4A 4412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.