Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.36 |
| ▸ | GPR3 | P46089 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20594275 | 0.90 | MAPT (0.40) | CES1TOP2ATOP2BGPR3ALDH1A1 | |
| SCHEMBL26332378 | 0.90 | GPR3 (0.39) | CES1GPR3ALDH1A1MAPTGAA | |
| SCHEMBL26332445 | 0.85 | CHRM5 (0.38) | CES1ALDH1A1MAPTGAAPKM | |
| SCHEMBL12148955 | 0.83 | GPR3 (0.44) | CES1GPR3ALDH1A1MAPTGAA | |
| SCHEMBL22109487 | 0.82 | GPR3 (0.39) | CES1GPR3ALDH1A1MAPTGAA | |
| SCHEMBL22109135 | 0.81 | ALDH1A1 (0.33) | GPR3ALDH1A1MAPTGAAMEN1 | |
| SCHEMBL15779912 | 0.79 | GPR3 (0.41) | CES1GPR3ALDH1A1MAPTGAA | |
| SCHEMBL22109130 | 0.79 | MAPT (0.39) | ALDH1A1MAPTGAAPKMMEN1 | |
| SCHEMBL12149351 | 0.78 | GPR3 (0.41) | CES1GPR3ALDH1A1MAPTGAA | |
| SCHEMBL12198207 | 0.78 | ALDH1A1 (0.37) | GPR3ALDH1A1MAPTGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767299-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-09-26 | — | — | US | disclosed |
| US-11767299-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-09-26 | — | — | US | disclosed |
| US-20200190039-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190039-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EFNA1, EPCAM | CES1 2590/4885TOP2A 3973/4885TOP2B 3020/4885 |
| US-11767299-B2 | Materials for organic electroluminescent devices | L1CAM, EFNA1, EPCAM | CES1 2590/4885TOP2A 3973/4885TOP2B 3020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.