Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 6/20 | 0.38 |
| ▸ | USP8 | P40818 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20594275 | 0.94 | MAPT (0.40) | CHRM5MAPTTDP1ALDH1A1GAA | |
| SCHEMBL22109136 | 0.85 | CES1 (0.39) | CHRM5MAPTTDP1ALDH1A1GAA | |
| SCHEMBL22109487 | 0.85 | GPR3 (0.39) | MAPTTDP1ALDH1A1GAAPKM | |
| SCHEMBL12148955 | 0.81 | GPR3 (0.44) | MAPTTDP1ALDH1A1GAAPKM | |
| SCHEMBL15779912 | 0.80 | GPR3 (0.41) | MAPTTDP1ALDH1A1GAAPKM | |
| SCHEMBL12198207 | 0.78 | ALDH1A1 (0.37) | MAPTTDP1ALDH1A1GAAPKM | |
| SCHEMBL26332378 | 0.78 | GPR3 (0.39) | MAPTTDP1ALDH1A1GAAPKM | |
| SCHEMBL15779904 | 0.78 | GPR3 (0.39) | MAPTKDM4ETDP1ALDH1A1GAA | |
| SCHEMBL20779040 | 0.77 | GPR3 (0.42) | MAPTTDP1ALDH1A1GAAPKM | |
| SCHEMBL24757209 | 0.77 | GPR3 (0.38) | MAPTTDP1ALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767299-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767299-B2 | Materials for organic electroluminescent devices | L1CAM, EFNA1, EPCAM | CHRM5 584/4885USP8 4862/4885MAPT 1878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.