Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.37 |
| ▸ | CHRNG | P07510 | 2/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRND | Q07001 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095398 | 0.84 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2OPRL1OPRM1 | |
| SCHEMBL22112324 | 0.81 | SLC6A4 (0.62) | SLC6A3SLC6A4SLC6A2OPRL1OPRM1 | |
| SCHEMBL22112097 | 0.81 | OPRM1 (0.49) | SLC6A3SLC6A4SLC6A2OPRL1OPRM1 | |
| SCHEMBL3407429 | 0.79 | OPRL1 (0.69) | OPRL1OPRM1OPRK1 | |
| SCHEMBL21780752 | 0.70 | SLC6A3 (0.43) | SLC6A3SLC6A4SLC6A2OPRL1OPRM1 | |
| SCHEMBL22112042 | 0.69 | OPRM1 (0.44) | SLC6A3SLC6A4SLC6A2OPRL1OPRM1 | |
| SCHEMBL19094002 | 0.69 | OPRL1 (0.48) | SLC6A3SLC6A4SLC6A2OPRL1OPRM1 | |
| SCHEMBL19094000 | 0.69 | OPRL1 (0.48) | SLC6A3SLC6A4SLC6A2OPRL1OPRM1 | |
| SCHEMBL28670092 | 0.69 | SLC6A4 (0.48) | SLC6A3SLC6A4SLC6A2OPRL1OPRM1 | |
| SCHEMBL19120357 | 0.68 | SLC6A3 (0.43) | SLC6A3SLC6A4SLC6A2OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020120539-A1 | NEW PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2020-06-18 | — | — | WO | disclosed |