SCHEMBL22112657

SCHEMBL22112657

CNn1cccc(-c2ccccc2)c1=N

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A2 O94788 1/20 0.34
ALDH1A3 P47895 1/20 0.34
ALDH1A1 P00352 4/20 0.33
HSD17B10 Q99714 3/20 0.33
HPGD P15428 1/20 0.33
BCL2L1 Q07817 1/20 0.33
CYP2A6 P11509 1/20 0.33
MAPK1 P28482 1/20 0.33
CLK4 Q9HAZ1 2/20 0.33
RET P07949 1/20 0.33
MET P08581 1/20 0.33
LTK P29376 1/20 0.33
GRK5 P34947 1/20 0.33
CDK8 P49336 1/20 0.33
RPS6KA3 P51812 1/20 0.33
MST1R Q04912 1/20 0.33
TYRO3 Q06418 1/20 0.33
DYRK1A Q13627 1/20 0.33
LRRK2 Q5S007 1/20 0.33
ALK Q9UM73 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22112809 0.67
SCHEMBL19441243 0.62
SCHEMBL21447 0.61 ALDH1A1 (0.61) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL2361430 0.61 ALDH1A1 (0.61) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Benzene SCHEMBL28035419 0.61 ALDH1A1 (0.61) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL19787487 0.60 TDO2 (0.44) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL1039296 0.60 ALDH1A1 (0.50) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL24513383 0.60 BRD4 (0.33) ALDH1A1TDO2KDM4ESLC6A4BACE1
Methyl Alcohol SCHEMBL27490755 0.60 ALDH1A1 (0.60) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Methylamine SCHEMBL27430084 0.60 ALDH1A1 (0.60) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020122614-A1 ORGANIC COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 두산솔루스 주식회사 2020-06-18 WO disclosed