Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18509790 | 0.87 | ESR2 (0.42) | TDO2ALDH1A1HSD17B10HPGDCYP2A6 | |
| SCHEMBL6077764 | 0.87 | MAPT (0.44) | TDO2ALDH1A1HSD17B10MAPK1HPGD | |
| SCHEMBL18634828 | 0.85 | ADORA2B (0.41) | TDO2ALDH1A1HSD17B10MAPK1HPGD | |
| SCHEMBL3789741 | 0.85 | ALDH1A1 (0.56) | TDO2ALDH1A1HSD17B10MAPK1HPGD | |
| SCHEMBL18290885 | 0.81 | ACLY (0.42) | TDO2ALDH1A1TSHRESR2TDP1 | |
| SCHEMBL3362915 | 0.80 | HNF4A (0.58) | ALDH1A1HSD17B10MAPK1ALOX15HNF4A | |
| SCHEMBL28049390 | 0.79 | ESR2 (0.44) | TDO2ALDH1A1MAPK1CYP2A6TSHR | |
| SCHEMBL26817540 | 0.79 | CYP3A4 (0.42) | ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL1039296 | 0.75 | ALDH1A1 (0.50) | TDO2ALDH1A1HSD17B10MAPK1HPGD | |
| SCHEMBL3212011 | 0.75 | ALDH1A1 (0.48) | TDO2ALDH1A1HSD17B10MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4016659-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2022-06-22 | — | — | EP | disclosed |
| WO-2018013943-A1 | HALOGEN-CONTAINING METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-01-18 | — | — | WO | disclosed |