SCHEMBL24513383

SCHEMBL24513383

C/N=c1/c(-c2ccccc2)cc(-c2ccccc2)cn1NC

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.33
KDM4E B2RXH2 2/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
IKBKB O14920 1/20 0.32
CHUK O15111 1/20 0.32
BACE1 P56817 1/20 0.31
SLC22A2 O15244 1/20 0.31
SLC22A1 O15245 1/20 0.31
SLC22A3 O75751 1/20 0.31
SLC6A4 P31645 1/20 0.31
ALDH1A1 P00352 2/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
HPRT1 P00492 1/20 0.30
PTGS1 P23219 1/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18290885 0.62 ACLY (0.42) NPC1MAPTRAB9ASMN1; SMN2IKBKB
Biphenyl SCHEMBL6943550 0.61 ALDH1A1 (0.69) NPC1MAPTRAB9ASMN1; SMN2SLC22A2
SCHEMBL22112657 0.60 ALDH1A2 (0.34) KDM4EBACE1SLC6A4ALDH1A1TDO2
SCHEMBL21703859 0.60 HTR6 (0.49) BRD4KDM4ENPC1MAPTRAB9A
SCHEMBL24280039 0.60 HTR6 (0.49) BRD4KDM4ENPC1MAPTRAB9A
SCHEMBL20663065 0.59 PTGS1 (0.58) KDM4ENPC1MAPTRAB9ASMN1; SMN2
Biphenyl SCHEMBL27543986 0.59 ALDH1A1 (0.64) KDM4ENPC1MAPTRAB9ASMN1; SMN2
Biphenyl SCHEMBL27334887 0.59 ALDH1A1 (0.64) NPC1MAPTRAB9ASMN1; SMN2SLC22A2
Biphenyl SCHEMBL2598157 0.58 ALDH1A1 (0.75) NPC1MAPTRAB9ASMN1; SMN2SLC22A2
Biphenyl SCHEMBL3990404 0.58 ALDH1A1 (0.75) NPC1MAPTRAB9ASMN1; SMN2BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022124858-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 솔루스첨단소재 주식회사 2022-06-16 WO disclosed