Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.43 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16127947 | 0.80 | FFAR1 (0.49) | FFAR1ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL16088671 | 0.80 | TRPV1 (0.56) | FFAR1SMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL17538521 | 0.80 | FFAR1 (0.52) | FFAR1ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL16088651 | 0.73 | ALDH1A1 (0.58) | FFAR1SMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL27464184 | 0.72 | TYK2 (0.68) | SMN1; SMN2HPGDALDH1A1POLB | |
| SCHEMBL12284610 | 0.71 | FFAR1 (0.75) | FFAR1ADRB3SMN1; SMN2KDM4ELMNA | |
| SCHEMBL29400205 | 0.70 | ALDH1A1 (0.63) | KDM4ELMNAHPGDALDH1A1POLB | |
| SCHEMBL80110 | 0.70 | ALDH1A1 (0.63) | KDM4ELMNAHPGDALDH1A1POLB | |
| SCHEMBL7190666 | 0.69 | TRPV1 (0.61) | SMN1; SMN2KDM4EHPGDALDH1A1POLB | |
| SCHEMBL6841680 | 0.69 | ALDH1A1 (0.72) | KDM4ELMNAHPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11045476-B2 | Compounds and methods for inducing chondrogenesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-06-29 | — | — | US | disclosed |
| US-20200188407-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | THE SCRIPPS RESEARCH INSTITUTE | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11045476-B2 | Compounds and methods for inducing chondrogenesis | COL2A1, BMP4, COL1A1 | FFAR1 2848/4885ITGB1 2770/4885ITGA4 3063/4885 |
| US-20200188407-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | COL2A1, BMP4, COL1A1 | FFAR1 2848/4885ITGB1 2770/4885ITGA4 3063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.