Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | FOS | P01100 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | JUN | P05412 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7559299 | 0.74 | TRPV1 (0.41) | CA1ALOX5CA12CA7CA9 | |
| SCHEMBL16200913 | 0.74 | ALOX5 (0.39) | CA1ALOX5CA12CA7CA9 | |
| SCHEMBL4738884 | 0.73 | ALOX5 (0.40) | CA1ALOX5CA12CA7CA9 | |
| SCHEMBL9059464 | 0.73 | ALDH1A1 (0.40) | CA1ALOX5CA12CA7CA9 | |
| SCHEMBL11231888 | 0.71 | TRPV1 (0.37) | CA1ALOX5CA12CA7CA9 | |
| SCHEMBL9103459 | 0.71 | ALOX5 (0.51) | ALOX5TRPV1 | |
| SCHEMBL27688413 | 0.70 | ALOX5 (0.33) | CA1ALOX5CA12CA7CA9 | |
| SCHEMBL2820470 | 0.70 | HMGCR (0.44) | ALOX5TRPV1 | |
| SCHEMBL6636441 | 0.70 | PTGS2 (0.46) | CA1ALOX5CA9CA2 | |
| SCHEMBL30290818 | 0.69 | TRPV1 (0.40) | CA1ALOX5CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635777-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2012-06-06 | — | — | EP | claimed |
| EP-1952843-B1 | Photostable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom | MERCK PATENT GMBH (DE) | 2011-07-27 | — | — | EP | disclosed |