Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30290818 | 0.90 | TRPV1 (0.40) | TRPV1CA1CA12CA7CA9 | |
| SCHEMBL11231888 | 0.89 | TRPV1 (0.37) | TRPV1CA1CA12CA7CA9 | |
| SCHEMBL2820470 | 0.87 | HMGCR (0.44) | TRPV1POLBALOX5GABRA1GABRB2 | |
| SCHEMBL12504376 | 0.83 | TRPV1 (0.43) | TRPV1CA1CA12CA7CA9 | |
| SCHEMBL15427430 | 0.83 | PTGS2 (0.37) | DRD2GABRA1GABRB2 | |
| SCHEMBL1173287 | 0.83 | ALOX5 (0.44) | POLBALOX5GABRA1GABRB2 | |
| SCHEMBL29385020 | 0.82 | ESR1 (0.39) | ESR1ESR2GABRA1GABRB2BACE1 | |
| SCHEMBL29719141 | 0.82 | GABRA1 (0.46) | TRPV1CA1CA12CA7CA9 | |
| SCHEMBL19463402 | 0.80 | TRPV1 (0.41) | TRPV1CA1CA12CA7CA9 | |
| SCHEMBL16200913 | 0.80 | ALOX5 (0.39) | CA1CA12CA7CA9CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002013779-A1 | SKIN LIGHTENING AGENTS | ZYLEPSIS LIMITED (GB) | 2002-02-21 | — | — | WO | disclosed |