SCHEMBL2211620

SCHEMBL2211620

Cc1ccc(N(c2ccc(-c3cc(C(C)C)c4ccc5c(-c6ccc(N(c7ccc(C)c(C)c7)c7ccc(C)c(C)c7)cc6)cc(C(C)C)c6ccc3c4c56)cc2)c2ccc(C)c(C)c2)cc1C

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12433909 0.84 ALDH1A1 (0.34)
SCHEMBL2208597 0.81 L3MBTL1 (0.34) LMNA
SCHEMBL17263976 0.81 HSP90AA1 (0.31)
SCHEMBL18079874 0.80 KDM4E (0.31)
SCHEMBL17264032 0.79
SCHEMBL17263989 0.78 RARA (0.30)
SCHEMBL17264047 0.77 HSD17B1 (0.30)
SCHEMBL21870399 0.77
SCHEMBL17264031 0.75 KDM4E (0.31)
SCHEMBL10353730 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7981523-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-07-19 US claimed
US-7981523-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-07-19 US disclosed
US-7981523-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-07-19 US disclosed