SCHEMBL22117404

SCHEMBL22117404

N=C(N)NCCC[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 3/20 0.51
▸ F2R P25116 2/20 0.50
▸ CPB2 Q96IY4 2/20 0.50
▸ NPY4R P50391 6/20 0.49
▸ NPY1R P25929 4/20 0.49
▸ NPY2R P49146 4/20 0.49
▸ NPY5R Q15761 4/20 0.49
▸ IL23R Q5VWK5 1/20 0.49
▸ OPRM1 P35372 1/20 0.48
▸ MMP1 P03956 2/20 0.48
▸ MMP2 P08253 2/20 0.48
▸ MMP3 P08254 2/20 0.48
▸ CHRNB2 P17787 1/20 0.47
▸ CHRNB4 P30926 1/20 0.47
▸ CHRNA3 P32297 1/20 0.47
▸ CHRNA4 P43681 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22117405 1.00 KISS1R (0.51) KISS1RF2RCPB2NPY4RNPY1R
SCHEMBL22117544 0.99 NPY4R (0.50) KISS1RF2RCPB2NPY4RNPY1R
SCHEMBL22117546 0.99 NPY4R (0.50) KISS1RF2RCPB2NPY4RNPY1R
SCHEMBL29641083 0.93 NPY4R (0.53) KISS1RF2RNPY4RNPY1RNPY2R
SCHEMBL22117841 0.93 NPY4R (0.47) KISS1RF2RNPY4RNPY1RNPY2R
SCHEMBL22117843 0.93 NPY4R (0.47) KISS1RF2RNPY4RNPY1RNPY2R
SCHEMBL22117572 0.92 NPY4R (0.54) F2RNPY4RNPY1RNPY2RNPY5R
SCHEMBL22117571 0.92 NPY4R (0.54) F2RNPY4RNPY1RNPY2RNPY5R
SCHEMBL28637452 0.91 OPRM1 (0.45) KISS1RCPB2NPY4RNPY1RNPY2R
SCHEMBL28637450 0.91 OPRM1 (0.45) KISS1RCPB2NPY4RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404300-B2 Mitochondria-targeting peptides STEALTH BIOTHERAPEUTICS INC. (US) 2025-09-02 — — US disclosed
EP-3898652-A1 MITOCHONDRIA-TARGETING PEPTIDES Stealth Biotherapeutics Corp (MC) 2021-10-27 — — EP disclosed
WO-2020131282-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS CORP. (MC) 2020-06-25 — — WO disclosed
WO-2020131282-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS CORP. (MC) 2020-06-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404300-B2 Mitochondria-targeting peptides SSBP1, HSPE1, IMMT KISS1R 4532/4885F2R 2422/4885CPB2 1060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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