SCHEMBL22117841

SCHEMBL22117841

N=C(N)NCCC[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CC1CCOCC1)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 8/20 0.47
▸ NPY1R P25929 5/20 0.47
▸ NPY2R P49146 4/20 0.47
▸ NPY5R Q15761 4/20 0.47
▸ OPRM1 P35372 1/20 0.47
▸ KISS1R Q969F8 3/20 0.45
▸ OPRL1 P41146 3/20 0.44
▸ IL23R Q5VWK5 1/20 0.44
▸ F2R P25116 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22117843 1.00 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL22117542 0.94 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL22117540 0.94 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL22117546 0.94 NPY4R (0.50) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL22117544 0.94 NPY4R (0.50) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL22117404 0.93 KISS1R (0.51) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL22117405 0.93 KISS1R (0.51) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL28645300 0.93 OPRM1 (0.43) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL28645296 0.93 OPRM1 (0.43) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL31679033 0.90 CTSL (0.48) NPY4RNPY1RNPY2RNPY5RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404300-B2 Mitochondria-targeting peptides STEALTH BIOTHERAPEUTICS INC. (US) 2025-09-02 — — US disclosed
EP-3898652-A1 MITOCHONDRIA-TARGETING PEPTIDES Stealth Biotherapeutics Corp (MC) 2021-10-27 — — EP disclosed
WO-2020131282-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS CORP. (MC) 2020-06-25 — — WO disclosed
WO-2020131282-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS CORP. (MC) 2020-06-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404300-B2 Mitochondria-targeting peptides SSBP1, HSPE1, IMMT NPY4R 2540/4885NPY1R 2382/4885NPY2R 2383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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