SCHEMBL22117579

SCHEMBL22117579

CC(C)(C)OC(=O)NC(Cc1c(F)c(F)c(F)c(F)c1F)C(=O)NC(CCCCNC(=O)O)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CTSS P25774 4/20 0.58
▸ REN P00797 3/20 0.42
▸ CCKBR P32239 2/20 0.41
▸ CTSK P43235 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22117578 1.00 CTSS (0.58) CTSSRENCCKBRCTSK
SCHEMBL22117577 0.94 CTSS (0.52) CTSSCCKBR
SCHEMBL22117580 0.94 CTSS (0.52) CTSSCCKBR
SCHEMBL22117410 0.88 REN (0.48) CTSSRENCCKBRCTSK
SCHEMBL22117409 0.88 REN (0.48) CTSSRENCCKBRCTSK
SCHEMBL31679029 0.86 MAPT (0.54) CTSSRENCCKBR
SCHEMBL28652456 0.85 CTSS (0.53) CTSSRENCCKBRCTSK
SCHEMBL28652455 0.85 CTSS (0.53) CTSSRENCCKBRCTSK
SCHEMBL22117412 0.84 REN (0.59) CTSSRENCCKBRCTSK
SCHEMBL22117411 0.84 REN (0.59) CTSSRENCCKBRCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3898652-A1 MITOCHONDRIA-TARGETING PEPTIDES Stealth Biotherapeutics Corp (MC) 2021-10-27 — — EP disclosed
WO-2020131282-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS CORP. (MC) 2020-06-25 — — WO disclosed
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