Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105482 | 0.74 | MEN1 (0.31) | — | |
| SCHEMBL11104823 | 0.71 | MGLL (0.37) | ALDH1A1TDP1 | |
| SCHEMBL11109281 | 0.70 | MAPK1 (0.32) | — | |
| SCHEMBL11366516 | 0.70 | GAA (0.42) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11196595 | 0.69 | ALDH1A1 (0.31) | ALDH1A1POLBL3MBTL1 | |
| SCHEMBL11467166 | 0.69 | GAA (0.40) | ALDH1A1POLB | |
| SCHEMBL11449432 | 0.69 | ALDH1A1 (0.40) | ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL9741206 | 0.67 | HTR1A (0.34) | ALDH1A1 | |
| SCHEMBL11105201 | 0.66 | CCND1 (0.36) | ALDH1A1POLB | |
| SCHEMBL21816355 | 0.66 | MGLL (0.42) | ALDH1A1POLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937678-B1 | HIV INTEGRASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2011-07-27 | — | — | EP | disclosed |