Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873099 | 0.82 | CYP2C19 (0.53) | SERPINE1ALDH1A1TDP1CYP2C19TSHR | |
| SCHEMBL22118149 | 0.80 | TSHR (0.47) | ALDH1A1CYP2C19TSHRMGLLBCL2 | |
| SCHEMBL7002879 | 0.79 | CYP2C19 (0.49) | ALOX5PDK1OPRK1OPRM1OPRD1 | |
| SCHEMBL28846934 | 0.75 | HSP90AB1 (0.51) | PDK1LMNATSHRBCL2L1 | |
| SCHEMBL7148219 | 0.73 | TSHR (0.54) | ALDH1A1CYP2C19LMNACYP1A2POLB | |
| SCHEMBL2957378 | 0.72 | CYP2C19 (0.64) | OPRM1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1550059 | 0.72 | ALDH1A1 (0.50) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL1672672 | 0.72 | CRHBP (0.58) | PDK1OPRK1OPRM1OPRD1MEN1 | |
| SCHEMBL9423649 | 0.72 | CHRM2 (0.47) | PDK1OPRK1OPRM1ALDH1A1MAPT | |
| Bromide SCHEMBL9175713 | 0.71 | ALDH1A1 (0.48) | MEN1ALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246112-B1 | PREPARATION OF DIAMINO- AND DIALKYLAMINOBENZENEDIOLS | THE DOW CHEMICAL COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4806688-A | Preparation of diamino- and dialkylaminobenzenediols | THE DOW CHEMICAL COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0246112-A1 | Preparation of diamino- and dialkylaminobenzenediols | THE DOW CHEMICAL COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |
| WO-1987006930-A1 | PREPARATION OF DIAMINO- AND DIALKYLAMINOBENZENEDIOLS | THE DOW CHEMICAL COMPANY (US) | 1987-11-19 | — | — | WO | disclosed |